The smallpox vaccine was different from the shots most people receive today.
Doctors used a special two-pronged needle dipped into a vaccine solution containing a virus called Vaccinia. The skin was pricked several times in a small area on the upper arm.
After the vaccination, the area went through several stages:
1. Mild Swelling
Within hours, the spot might become slightly swollen.
2. A Small Bump Appears
Several days later, a raised bump forms.
3. Blister Formation
The bump grows into a blister filled with fluid.
4. Scab and Healing
The blister dries out and forms a scab.
5. Permanent Scar
When the scab falls off, a small circular scar remains.
The entire process could take several weeks, and in some cases the area would go through more than one cycle of healing before settling permanently.
Why Is the Scar Usually Round?
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